Let KAYAK do the searching
Based on KAYAK hotel searches, the most popular destination is St. Louis (43% of total searches to Missouri). The next most popular destinations are Branson (29%) and Osage Beach (14%). Searches for hotels in Cape Girardeau (14%) are also popular.
KAYAK users have found double rooms in Missouri for as cheap as R692 (Branson) in the last 3 days. The average price is R3 195.